NAD+ [500mg]

Description

Chemical Identity & Molecular Composition

Chemical Name: Nicotinamide Adenine Dinucleotide (Oxidized Form, NAD⁺)
Chemical Class: Pyridine nucleotide coenzyme
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: ~663.43 g/mol
CAS Number: 53-84-9

Structural Characteristics

Nicotinamide adenine dinucleotide (NAD⁺) is a naturally occurring dinucleotide composed of two nucleotides joined through their phosphate groups—one containing an adenine base and the other containing nicotinamide. The molecule exists in an oxidized (NAD⁺) and reduced (NADH) redox pair, enabling reversible electron transfer in biochemical systems.

The nicotinamide moiety serves as the redox-active center, while the adenine ribose phosphate provides structural stability and enzyme recognition. NAD⁺ is water-soluble and commonly supplied as a lyophilized powder for controlled in vitro research applications.

Biochemical Function & Mechanistic Activity (Research Context Only)

Redox Coenzyme Activity

In vitro research utilizes NAD⁺ as a central electron carrier in oxidation–reduction reactions. NAD⁺ accepts electrons to form NADH, facilitating enzymatic studies of metabolic and energy-related pathways.

Enzyme Cofactor Function

NAD⁺ functions as a required cofactor in laboratory studies involving dehydrogenases, oxidoreductases, and other NAD⁺-dependent enzymes.

Substrate for NAD⁺-Consuming Enzymes

Researchers investigate NAD⁺ as a substrate in cellular signaling studies involving sirtuins, poly(ADP-ribose) polymerases (PARPs), and NAD⁺-dependent deacetylation and ADP-ribosylation reactions under controlled laboratory conditions.

Cellular Metabolism Models

In vitro systems use NAD⁺ to study cellular redox balance, metabolic flux, and energy-related biochemical pathways. All findings are limited to non-clinical laboratory research and do not imply therapeutic use.

Research Applications

NAD⁺ is commonly used in laboratory studies to investigate:

• Redox reactions and electron transfer mechanisms

• Enzyme kinetics involving NAD⁺-dependent oxidoreductases

• Cellular metabolism and energy-related biochemical pathways

• Sirtuin and PARP enzymatic activity (in vitro)

• Redox balance and coenzyme cycling

• Structure-function relationships of pyridine nucleotides

All applications are intended strictly for non-clinical, in vitro research use only.

Product Specifications

Form & Stability

• Format: Lyophilized nucleotide coenzyme

• Purity: ≥ 98% (HPLC validated)

• Appearance: White to off-white crystalline or lyophilized powder

• Solubility: Readily soluble in water and compatible laboratory buffers

• Stability: Stable in lyophilized form; sensitive to moisture, heat, and light after reconstitution

Storage

• Store at –20°C

• Protect from light and humidity

• Avoid repeated freeze–thaw cycles

• Use aseptic laboratory handling procedures

Packaging

• Provided in sterile, sealed vials

• Labeled with batch number, lot, purity, and molecular identification

• Manufactured under controlled laboratory conditions to ensure research-grade consistency

Composition

Each vial contains:

• 5 mg, 10 mg, or 20 mg of high-purity Nicotinamide Adenine Dinucleotide (NAD⁺)

• No fillers, additives, or excipients

• Lyophilized to maintain molecular stability and reproducible research outcomes

Intended Use

This compound is intended exclusively for laboratory research, including:

• Redox and electron-transfer studies

• Enzyme kinetics and cofactor dependency assays

• Cellular metabolism and biochemical pathway research

• NAD⁺-dependent enzymatic mechanism studies

• Structure-function analysis of nucleotide coenzymes

Not for human or animal consumption, medical, therapeutic, cosmetic, or diagnostic applications.

Research-Only Disclaimer

This product is strictly for research use only. It is NOT intended for:

• Human or animal consumption

• Therapeutic, cosmetic, or wellness use

• Clinical or diagnostic applications

• In vivo studies

Proper laboratory handling procedures and safety protocols are required.