MT-2 Melanotan [10mg]

Description

Chemical Identity & Molecular Composition

Chemical Name: [Nle4, D-Phe7]-α-Melanocyte-Stimulating Hormone (Melanotan II)
Peptide Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular Formula: C₅₀H₆₉N₁₃O₉
Molecular Weight: 1024.2 g/mol
Peptide Class: Synthetic melanocortin receptor agonist peptide
CAS Number: 121062-08-6

Structural Characteristics

MT-2 Melanotan is a synthetic cyclic peptide analog of the natural α-melanocyte-stimulating hormone (α-MSH). Its cyclic structure is formed through an intramolecular bond between the side chain of aspartic acid and the lysine residue, creating a stable ring that enhances receptor binding and resistance to enzymatic degradation. The peptide includes modified residues, such as norleucine (Nle) and D-phenylalanine (D-Phe), to improve stability and receptor specificity in research studies. MT-2 binds to melanocortin receptors, enabling investigation of pigmentation and signaling pathways in controlled laboratory experiments.

Biochemical Function & Mechanistic Activity (Research Context Only)

1. Receptor Binding & Signaling
   MT-2 interacts with melanocortin receptors (MC1R, MC3R, MC4R, MC5R) in experimental models, enabling researchers to study receptor-mediated signaling pathways. It is widely investigated for its role in melanin synthesis, pigmentation signaling, and downstream cyclic AMP (cAMP) activation.

2. Pigmentation & Melanocyte Activity
   In vitro studies explore MT-2’s influence on melanocytes and pigment production, including melanin synthesis pathways and melanosome regulation. Researchers also study its effect on melanocyte proliferation and cellular response to UV-related pathways.

3. Cellular & Metabolic Pathways
   MT-2 is examined for potential interactions with metabolic signaling and melanocortin receptor-mediated processes, including modulation of intracellular signaling cascades, oxidative stress response, and peptide-receptor kinetics.

4. Research Mechanisms & Experimental Outcomes
   Studies investigate MT-2 for pigmentation regulation, melanocyte biology, receptor activation dynamics, and peptide stability. All mechanistic insights are strictly limited to controlled laboratory research and are not therapeutic interpretations.

Research Applications

MT-2 Melanotan is utilized in laboratory research for:

• Melanocortin receptor activity studies

• Melanin synthesis and pigmentation research

• Cellular signaling and receptor binding kinetics

• Melanocyte biology and proliferation studies

• Peptide stability and structure-function analyses

• In vitro cellular modeling of UV response pathways

All applications are intended for non-clinical, in vitro research use only.

Product Specifications

Form & Stability
Format: Lyophilized cyclic peptide
Purity: ≥ 98% (HPLC validated)
Appearance: White to off-white lyophilized powder
Solubility: Water-soluble; optimal in sterile aqueous buffers
Stability: High stability in lyophilized form; sensitive to moisture and prolonged light exposure

Storage
Store at –20°C
Protect from light and humidity
Avoid repeated freeze–thaw cycles
Use aseptic laboratory handling practices

Packaging
Provided in sterile, sealed vials
Labeled with batch, lot, purity, and molecular identification
Manufactured under controlled laboratory conditions for research-grade integrity

Composition

Each vial contains:
10mg of high-purity MT-2 Melanotan (synthetic cyclic peptide)
No fillers, additives, or excipients
Lyophilized for maximum stability and reproducible research results

Intended Use

This peptide is intended exclusively for laboratory research, including:

• In vitro biochemical studies

• Receptor signaling assays

• Cellular and molecular biology experiments

• Analytical research and peptide characterization

Not for human or animal consumption, medical, therapeutic, or cosmetic applications.

Research-Only Disclaimer

This product is strictly for research use only. It is NOT intended for:

• Human or animal consumption

• Therapeutic or cosmetic use

• Clinical or diagnostic applications

• In vivo studies

Proper laboratory handling procedures and safety protocols are required.