Description
Chemical Identity & Molecular Composition
Chemical Name: Mitochondrial Open Reading Frame of the 12S rRNA–Derived Peptide (MOTS-C)
Peptide Sequence: M-S-Y-K-K-F-R-A-Q-L
Molecular Formula: C₅₁H₈₄N₂₀O₁₂
Molecular Weight: ~2174 g/mol
Peptide Class: Mitochondrial-derived signaling peptide
CAS Number: Not assigned (research peptide)
Structural Characteristics
MOTS-C is a synthetic linear peptide derived from a short open reading frame within the 12S mitochondrial rRNA. The peptide’s structure allows it to interact with cellular metabolic pathways in vitro, particularly those related to mitochondrial energy regulation. Its small, linear composition and water solubility make it ideal for laboratory studies examining cellular signaling, energy metabolism, and mitochondrial function.
Biochemical Function & Mechanistic Activity (Research Context Only)
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Mitochondrial Signaling
In research models, MOTS-C modulates mitochondrial function and energy production, influencing pathways involved in cellular metabolism and homeostasis. -
Cellular Energy Regulation
Laboratory studies investigate how MOTS-C impacts nutrient sensing, AMPK activation, and related energy balance pathways. -
Metabolic Pathways
Researchers study MOTS-C for its role in regulating glucose uptake, lipid metabolism, and mitochondrial biogenesis under controlled experimental conditions. -
Experimental Outcomes
MOTS-C is used in vitro to study mechanisms of metabolic regulation, cellular stress response, and mitochondrial signaling. All observations are limited to laboratory research and are not therapeutic claims.
Research Applications
MOTS-C is commonly used in laboratory studies to investigate:
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Mitochondrial signaling and function
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Cellular energy and metabolic regulation
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AMPK and nutrient-sensing pathways
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Glucose and lipid metabolism in experimental models
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Mitochondrial biogenesis and cellular stress responses
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Peptide signaling and receptor interactions
All applications are strictly for non-clinical, in vitro research use only.
Product Specifications
Form & Stability
Format: Lyophilized linear peptide
Purity: ≥ 98% (HPLC validated)
Appearance: White to off-white lyophilized powder
Solubility: Water-soluble; optimal in sterile laboratory buffers
Stability: High stability in lyophilized form; sensitive to moisture and light after reconstitution
Storage
Store at –20°C
Protect from light and humidity
Avoid repeated freeze–thaw cycles
Use proper laboratory handling procedures
Packaging
Provided in sterile, sealed vials
Labeled with batch, lot, purity, and molecular identification
Manufactured under controlled laboratory conditions for research-grade integrity
Composition
Each vial contains:
5mg or 10mg of high-purity MOTS-C (linear peptide)
No fillers, additives, or excipients
Lyophilized to ensure maximum stability and reproducible research outcomes
Intended Use
This peptide is intended exclusively for laboratory research, including:
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Mitochondrial and cellular energy studies
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Metabolic signaling pathway assays
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Nutrient-sensing and AMPK pathway research
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Cellular stress response experiments
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Peptide signaling and mitochondrial biology studies
Not for human or animal consumption, medical, therapeutic, cosmetic, or diagnostic applications.
Research-Only Disclaimer
This product is strictly for research use only. It is NOT intended for:
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Human or animal consumption
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Therapeutic or cosmetic use
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Clinical or diagnostic procedures
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In vivo studies
Proper laboratory handling procedures and safety protocols are required.
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