GHK-CU [100mg]

Description

Chemical Identity & Molecular Composition

Chemical Name: Glycyl-L-Histidyl-L-Lysine Copper (II) Complex
Peptide Sequence: GHK tripeptide chelated with divalent copper (Cu²⁺)
Molecular Formula (complex): C14H24N6O4 · Cu
Molecular Weight (approx.): 340.8 g/mol
Peptide Class: Copper-binding tripeptide (metallopeptide)
CAS Number: 89030-95-5

Structural Characteristics

GHK-Cu is a naturally occurring copper complex formed by the tripeptide glycyl-L-histidyl-L-lysine coordinated with a divalent copper ion (Cu²⁺). The peptide binds copper through the nitrogen atoms of the histidine imidazole ring and the terminal amine groups, forming a stable square-planar or distorted octahedral coordination complex in aqueous environments. This chelation confers structural stability and enables participation in copper-dependent biochemical interactions. GHK-Cu is water-soluble and is typically supplied as a lyophilized powder for controlled in vitro research applications.

Biochemical Function & Mechanistic Activity (Research Context Only)

Copper Transport and Chelation
In vitro research utilizes GHK-Cu as a model copper-binding peptide to study copper transport, sequestration, and bioavailability in biochemical systems.

Cell Signaling Modulation
Laboratory studies investigate GHK-Cu interactions with cellular signaling pathways associated with gene expression modulation, extracellular matrix dynamics, and cellular response mechanisms under controlled conditions.

Enzymatic and Redox-Related Activity
The copper-bound form of GHK enables examination of copper-dependent redox reactions and enzyme-associated processes in non-clinical research models.

Experimental Outcomes
GHK-Cu is used to study peptide–metal interactions, copper-mediated signaling mechanisms, and structure-function relationships of metallopeptides. All findings are limited strictly to in vitro research and do not represent therapeutic claims.

Research Applications

GHK-Cu is commonly used in laboratory studies to investigate:

Copper-binding and transport mechanisms
Metallopeptide structure-function relationships
Copper-dependent cellular signaling pathways
Extracellular matrix and protein interaction models
Gene expression modulation in controlled in vitro systems
Peptide–metal complex stability and kinetics

All applications are intended strictly for non-clinical, in vitro research use only.

Product Specifications

Form & Stability
Format: Lyophilized copper-chelated tripeptide
Purity: ≥ 98% (HPLC validated)
Appearance: Blue to blue-green lyophilized powder
Solubility: Water-soluble; compatible with standard laboratory buffers
Stability: Stable in lyophilized form; sensitive to moisture, light, and oxidation after reconstitution

Storage
Store at –20°C
Protect from light and humidity
Avoid repeated freeze–thaw cycles
Use aseptic laboratory handling procedures

Packaging

Provided in sterile, sealed vials
Labeled with batch number, lot, purity, and molecular identification
Manufactured under controlled laboratory conditions for research-grade integrity

Composition

Each vial contains:
5 mg, 10 mg, or 20 mg of high-purity GHK-Cu (copper-chelated tripeptide)
No fillers, additives, or excipients
Lyophilized to ensure maximum stability and reproducible research outcomes

Intended Use

This compound is intended exclusively for laboratory research, including:

Copper-binding and metallopeptide studies
Cell signaling and gene expression research (in vitro)
Peptide–metal interaction analysis
Copper-dependent biochemical pathway studies
Structure-function research of tripeptide copper complexes

Not for human or animal consumption, medical, therapeutic, cosmetic, or diagnostic applications.

Research-Only Disclaimer

This product is strictly for research use only. It is NOT intended for:

Human or animal consumption
Therapeutic, cosmetic, or wellness use
Clinical or diagnostic applications
In vivo studies

Proper laboratory handling procedures and safety protocols are required.