Description
Chemical Identity & Molecular Composition
Chemical Name: AOD-9604 (Tyr-hGH fragment 176-191)
Chemical Class: Modified C-terminal fragment of human growth hormone (hGH 176-191)
Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight: ~1815.1 g/mol
CAS Number: 221231-10-3
Structural Characteristics
AOD-9604 is a synthetic 16-amino acid peptide corresponding to the C-terminal region of human growth hormone (residues 176-191), with an added tyrosine at the N-terminus. “This modification, combined with a Cys7-Cys15 disulfide bridge, stabilizes the fragment while isolating the lipolytic domain of the parent hormone” from its broader growth-signaling activity.
The product comes as a lyophilized white powder at ≥98% purity (HPLC) and reconstitutes in sterile water. The compound is studied for its capacity to influence fat metabolism without the IGF-1 induction or insulin-sensitivity changes associated with full-length hGH.
Research Applications
Researchers examine this compound for:
•”Lipolytic pathway activation independent of growth hormone receptor signaling”
•Adipose tissue metabolism and fat oxidation mechanisms
•Obesity and metabolic syndrome modeling
•Effects on lipid profiles without IGF-1 or blood glucose modulation
•Cartilage and connective tissue regeneration in emerging studies
Storage & Handling
“Store lyophilized peptide at -20°C, protected from light and moisture.” After reconstituting with sterile water, maintain at 2-8°C and use within 14 days. Do not refreeze after reconstitution.
Disclaimer
This product is intended for laboratory research use only. It is not intended for human consumption, medical, therapeutic, or diagnostic use. All handling and use must comply with applicable laws and regulations.
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