HCG [10,000iu]

Description

Chemical Identity & Molecular Composition

Chemical Name: Human Chorionic Gonadotropin (HCG)
Peptide Sequence: Heterodimeric glycoprotein hormone consisting of an alpha (92 amino acids) and beta (145 amino acids) subunit
Molecular Formula (approx.): C₆₆₆H₁₀₄₆N₁₈₀O₂₀₀S₂₀ (glycosylated form varies)
Molecular Weight: ~36,700 g/mol (varies with glycosylation)
Peptide Class: Glycoprotein hormone
CAS Number: 9002-61-3

Structural Characteristics

HCG is a naturally occurring heterodimeric glycoprotein hormone composed of alpha and beta subunits. Its structure contains extensive glycosylation, which influences its stability, solubility, and receptor binding in laboratory research. HCG binds to luteinizing hormone/chorionic gonadotropin receptors (LHCGR) in experimental models, allowing investigation of endocrine signaling, cellular receptor activation, and downstream molecular pathways. HCG is supplied as a lyophilized powder for research use, ensuring stability and solubility for in vitro studies.

Biochemical Function & Mechanistic Activity (Research Context Only)

1. Receptor Binding & Signal Transduction
   HCG interacts with LHCGR in vitro, activating cyclic AMP (cAMP) and protein kinase A (PKA) signaling pathways. Laboratory models use this mechanism to study gonadotropin-mediated cellular responses.

2. Endocrine Pathway Modulation
   In research settings, HCG is used to examine steroidogenesis, receptor-ligand interactions, and the regulation of downstream signaling cascades involved in reproductive hormone pathways.

3. Cellular & Molecular Signaling
   Laboratory studies explore HCG’s influence on gene expression, protein synthesis, and cellular signaling within gonadal, adrenal, and other endocrine-related tissue models.

4. Experimental Mechanistic Insights
   HCG enables research into glycoprotein hormone-receptor dynamics, intracellular signaling, and hormone-mediated cellular processes. Observations are limited to controlled in vitro experiments and are not therapeutic claims.

Research Applications

HCG is commonly used in laboratory studies to investigate:

• LHCGR receptor binding and signaling pathways

• Steroidogenesis and hormonal regulation mechanisms

• Glycoprotein hormone-receptor kinetics

• Gene expression and protein synthesis in endocrine models

• Cellular signaling in gonadal and adrenal research

• Peptide glycosylation and structure-function relationships

All applications are intended strictly for in vitro, non-clinical research use only.

Product Specifications

Form & Stability
Format: Lyophilized glycoprotein hormone
Purity: ≥ 98% (HPLC validated)
Appearance: White to off-white lyophilized powder
Solubility: Water-soluble; optimal in sterile laboratory buffers
Stability: Stable in lyophilized form; sensitive to moisture, light, and temperature after reconstitution

Storage
Store at –20°C
Protect from light and humidity
Avoid repeated freeze–thaw cycles
Use aseptic laboratory handling procedures

Packaging
Provided in sterile, sealed vials
Labeled with batch, lot, purity, and molecular identification
Manufactured under controlled laboratory conditions for research-grade integrity

Composition

Each vial contains:
10,000 IU of high-purity Human Chorionic Gonadotropin (HCG)
No fillers, additives, or excipients
Lyophilized for maximum stability and reproducible research outcomes

Intended Use

This product is intended exclusively for laboratory research, including:

• LHCGR receptor signaling studies

• Endocrine pathway and hormone receptor assays

• Cellular signaling and protein expression research

• Glycoprotein hormone structure-function studies

• Steroidogenesis and molecular biology experiments

Not for human or animal consumption, medical, therapeutic, cosmetic, or diagnostic applications.

Research-Only Disclaimer

This product is strictly for research use only. It is NOT intended for:

• Human or animal consumption

• Therapeutic or cosmetic use

• Clinical or diagnostic applications

• In vivo studies

Proper laboratory handling procedures and safety protocols are required.