Retatrutide [30 mg]

$150.00

Retatrutide is a synthetic peptide studied in laboratory research for its role in metabolic regulation and multi-receptor signaling. It is designed to interact with several pathways involved in glucose metabolism, energy balance, and cellular function, making it a focus for controlled experimental studies.

In research, Retatrutide is studied for its potential to support metabolic signaling, energy regulation, and tissue function in laboratory models.

Researchers also explore its potential effects on:

  • Supporting receptor-mediated signaling and metabolic pathway activation in lab studies

  • Investigating cellular energy regulation and nutrient-sensing mechanisms

  • Studying tissue responses and cellular adaptation to metabolic changes

  • Exploring peptide stability, receptor interactions, and intracellular signaling dynamics

In stock

SKU: RT30 Category:

Description

Chemical Identity & Molecular Composition

Chemical Name: Retatrutide (LY3437943), Triple GIP, GLP-1, and Glucagon Receptor Agonist Peptide
Peptide Sequence: Synthetic linear peptide (modified with fatty acid acylation for albumin binding; sequence proprietary to research-grade specification)
Molecular Formula (approx.): C₂₄₀H₃₇₀N₆₇O₇₂
Molecular Weight (approx.): 5200 g/mol
Peptide Class: Multi-receptor agonist (GIP/GLP-1/Glucagon), linear acylated peptide
CAS Number: Not assigned (research peptide)

Structural Characteristics

Retatrutide is a synthetic linear peptide engineered to simultaneously activate glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors in vitro. The peptide contains fatty acid acylation on select lysine residues, allowing reversible albumin binding in laboratory systems. This modification increases peptide stability, prolongs receptor engagement, and enhances resistance to enzymatic degradation. Retatrutide is supplied as a lyophilized powder for research purposes, providing reproducibility and solubility for in vitro studies.

Biochemical Function & Mechanistic Activity (Research Context Only)

  1. Multi-Receptor Activation
    In research models, Retatrutide engages GIP, GLP-1, and glucagon receptors, activating cAMP-mediated signaling pathways for experimental evaluation of metabolic and endocrine effects.

  2. Extended Stability via Albumin Interaction
    Fatty acid acylation allows reversible binding to albumin in vitro, prolonging peptide presence and enabling extended receptor interaction studies.

  3. Cellular Signaling & Metabolic Pathways
    Researchers study Retatrutide’s effects on insulinotropic signaling, nutrient sensing, glucagon-mediated pathways, and energy metabolism in controlled laboratory experiments.

  4. Experimental Outcomes
    Retatrutide is used in vitro to investigate multi-receptor pharmacology, peptide-receptor kinetics, metabolic pathway modulation, and structure-function relationships. All findings are limited to laboratory research and are not therapeutic claims.

Research Applications

Retatrutide is commonly used in laboratory studies to investigate:

  • Dual and triple receptor signaling (GIP, GLP-1, glucagon)

  • cAMP and downstream metabolic signaling pathways

  • Peptide half-life and albumin-binding kinetics

  • Insulinotropic and glucagon-mediated cellular responses

  • Structure-function relationships of multi-receptor peptides

  • Nutrient-sensing and metabolic regulation in vitro

All applications are intended strictly for non-clinical, in vitro research use only.

Product Specifications

Form & Stability
Format: Lyophilized linear acylated peptide
Purity: ≥ 98% (HPLC validated)
Appearance: White to off-white lyophilized powder
Solubility: Water-soluble; optimal in sterile laboratory buffers
Stability: Stable in lyophilized form; sensitive to moisture, light, and temperature after reconstitution

Storage
Store at –20°C
Protect from light and humidity
Avoid repeated freeze–thaw cycles
Use aseptic laboratory handling procedures

Packaging
Provided in sterile, sealed vials
Labeled with batch, lot, purity, and molecular identification
Manufactured under controlled laboratory conditions for research-grade integrity

Composition

Each vial contains:
5mg, 10mg, or 20mg of high-purity Retatrutide (synthetic multi-receptor peptide)
No fillers, additives, or excipients
Lyophilized to ensure maximum stability and reproducible research outcomes

Intended Use

This compound is intended exclusively for laboratory research, including:

  • Multi-receptor signaling studies (GIP/GLP-1/Glucagon)

  • Metabolic and endocrine pathway research

  • Insulinotropic and glucagon-mediated assays

  • Peptide half-life and albumin-binding evaluation

  • In vitro nutrient-sensing and cellular metabolism studies

Not for human or animal consumption, medical, therapeutic, cosmetic, or diagnostic applications.

Research-Only Disclaimer

This product is strictly for research use only. It is NOT intended for:

  • Human or animal consumption

  • Therapeutic or cosmetic use

  • Clinical or diagnostic applications

  • In vivo studies

Proper laboratory handling procedures and safety protocols are required.