Selank [10mg]

$60.00

Selank is a synthetic heptapeptide analog of the immunomodulatory peptide tuftsin, developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is classified as a nootropic and anxiolytic peptide in research literature.

Researchers investigate Selank for:

  • Anxiolytic mechanisms without sedative effects
  • Cognitive function and memory formation pathways
  • Immunomodulatory and anti-inflammatory signaling
  • BDNF expression and neuroplasticity research
  • Monoamine neurotransmitter system modulation

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SKU: SK10 Category:

Description

Chemical Identity & Molecular Composition

Chemical Name: Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Chemical Class: Synthetic heptapeptide, tuftsin analog
Molecular Formula: C₃₃H₅₇N₁₁O₉
Molecular Weight: ~751.87 g/mol
CAS Number: 129954-34-3

Structural Characteristics

Selank is a synthetic peptide consisting of the tetrapeptide tuftsin (Thr-Lys-Pro-Arg) with an additional Pro-Gly-Pro sequence at the C-terminus. This C-terminal extension significantly enhances metabolic stability by providing resistance to peptidase degradation while preserving and extending the biological activity of the parent tuftsin sequence.

The peptide is supplied as a lyophilized white powder with purity ≥98% (HPLC). It is soluble in water and physiological buffers. Selank’s mechanism of action involves modulation of multiple neurotransmitter systems including serotonin, dopamine, and norepinephrine, as well as influence on BDNF and enkephalin expression.

Research Applications

Anxiolytic Research: Preclinical studies examine Selank’s anxiolytic properties, notably its ability to reduce anxiety-like behavior in animal models without the sedative, amnestic, or myorelaxant effects associated with benzodiazepines.

Cognitive & Nootropic Studies: Researchers investigate Selank’s effects on memory consolidation, learning, and attention, with particular focus on its influence on BDNF expression and hippocampal neuroplasticity.

Immunomodulation Research: As an analog of tuftsin (a known immunomodulator), Selank is studied for its effects on cytokine expression, immune cell activation, and inflammatory pathway modulation.

Neurotransmitter Studies: In vivo research examines Selank’s influence on serotonergic and dopaminergic system activity, including effects on monoamine metabolism and enkephalinase inhibition.

Storage & Handling

Store lyophilized peptide at -20°C, protected from light and moisture. Reconstitute with bacteriostatic water; store at 2-8°C and use within 21 days.

Disclaimer

This product is intended for laboratory research use only. It is not intended for human consumption, medical, therapeutic, or diagnostic use. All handling and use must comply with applicable laws and regulations.